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The Fugatesa family that lived in the hills of Kentucky, commonly known as the " Blue Fugates " [1] menn the Blue People of Kentuckyare notable for having been carriers of a genetic trait that led to the disease methemoglobinemiawhich gives sufferers blue-tinged skin. Martin Fugate and Elizabeth Smith [2] who had married and settled blue men kentucky Hazard, Kentucky in aroundwere both hlue of the recessive methemoglobinemia met-H gene, as was a nearby clan blue men kentucky whom the Fugates descendants intermarried.

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As a result, many descendants of the Fugates were born with met-H. Descendants with the disease gene continued to live in the areas around Blue men kentucky Creek and Ball Creek into the 20th century, eventually coming to the attention of the nurse Ruth Pendergrass and the hematologist Madison Cawein III, who made a detailed study of their condition and ancestry.

Blue men kentucky treated the family with methylene bluewhich eased their symptoms and reduced the blue coloring of their skin.

As travel became easier in the 20th century, and families spread out over wider areas, the prevalence of the recessive gene blue men kentucky the local population reduced, and with it the probability of inheriting the blue men kentucky. Benjamin Stacy, born inis the last known descendant of the Fugates to have been born exhibiting the characteristic blue color of the disease, and lost his blue skin mne as he grew older.

It has been speculated that some other American sufferers of inherited methemoglobinemia may also have had Fugate ancestors, but searches for direct links blue men kentucky so far proved inconclusive. From Wikipedia, the free encyclopedia.

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Family known for having blue skin. Archived from the original on January 22, Retrieved 10 May Phoenix, Arizona: Arizona Republic.

November 7, Retrieved 3 April — via Newspapers. Skin Bluer than Lake Louise".

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ABC News. Retrieved Davis January 19, The Paper.

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Archives of Internal Medicine. Retrieved from " https: American families. Hidden categories: Articles with short description All articles with unsourced statements Articles with unsourced statements from November Blue men kentucky Article Talk.

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